Newsletter
New High-bind plates from Porvair Sciences
The new Krystal™ Signum High Bind clear 96-well flat bottomed plates are designed to bind proteins, peptides, antibodies or other biomolecules onto the plate surface. These characteristics make them valuable for a wide range of applications such as ELISA, antibody screening/production, protein assays, peptide or hapten binding and general biomolecular immobilization. The two key characteristics are the high activation level and good clarity of the plate.
The new plates are made from high-grade polystyrene having a low background ideal for ELISA and fluorescence. The combination of a hydrophilic and hydrophobic surface allows binding a wide range of different molecules such as proteins, peptides and antibodies. All plates are tested for uniformity, stability and reproducibility and come in a standard SLAS/ANSI-format.
You are not convinced yet? Ask for a sample or use our launch offer to get a package of these plates with nearly 50 % off list price.
ELISA Kits and Components
Featured Kits, New Online Resources and Useful Tools
Innovative Research provides two new video resources on their website where they answer frequently asked questions about ELISA kits and explain the difference between active and total ELISA kits.
Highlights from their extensive portfolio are their numerous Coagulation Factor ELISA Kits to quantify clotting dynamics as well as their IgG Subclass ELISA Kits, ideal for profiling patient-specific immune responses.
ICL Inc. offers 14 Host Cell Proteins (HCP) ELISA kits for targeted and highly specific detection of CHO cells including PLBL2, a common CHO-derived impurity linked to immunogenicity and drug degradation or other key CHO-associated proteins like CTSA, LPLA2, Clusterin, and MMP-19 which are often missed by generic assays.
Detecting and removing HCP is essential when manufacturing biologic drugs to ensure safety and efficacy. Nowadays, generic host cell protein assays are often not sufficient anymore. Instead, protein specific ELISA kits in combination with orthogonal testing methods are preferred.
For accurate immunoassays, minimizing background signal and interference are crucial. Using a blocker during your assay can mitigate this problem, but choosing the correct blocker is not an easy task as the optimal blocker depends on antibodies used, assay format, and sample type.
Meridian Life Science offers a new sample pack BL-PK01 containing 6 different blockers: passive blockers like Mouse Serum and Mouse IgG, as well as Meridian’s specially formulated active blockers TRU Block™, TRU Block™ 2, TRU Block™ 3, and K-BLOCK™.
MOSS Inc. specialized in producing high-quality, liquid-stable substrates. Depending on your ELISA needs, you can choose from different chemiluminescent or chromogenic, soluble substrates for Horseradish peroxidase (HRP) and Alkaline phosphatase (AP), for example Chemi-HRP, Chemi-AP, TMB, ABTS or p-NPP.
For TMB, several different compositions are available with varying reactivity and sensitivity. To find the optimal TMB substrate for your assay, you can now order the new TMB evaluation pack TMB-SK. This pack contains all available soluble TMB substrates as well as their diluents. More information can be found in our brochure.