Dunn Labortechnik presents the innovative ECIS® Z-Theta device from Applied BioPhysics for impedance measurement of cell cultures.
The device continuously collects information about cells without labelling those. Cells remain in the incubator during measurement which prevents reactions due to stress.
The system can be used for a wide range of applications such as barrier function, cell proliferation, migration or cytotoxicity by measuring of up to 11 frequencies in parallel. The measurement can be done in 16-well format (2 x 8 wells) or for high throughput in 96-well format.
A special application of the ECIS® Z-Theta is the patented wound healing module. This tool enables the user to wound cells during measurement without taking them out of the incubator. By using an electrical current, wound size and locations are always the same making it highly reproducible even among different users which is a big advantage in comparison to classical scratch assays.
The wounding is done by passing a high current through the electrodes on which the cells are growing and killing these. This allows a high repetition and reproducibility in comparison to classic scratch assays.
The wound healing module can also be regulated to allow electroporation of cells. Instead of killing the cells, the current is reduced in a way that makes the cell membranes porous while keeping the cells intact.
For further information about the ECIS® Z-Theta from Applied BioPhysics please contact us or visit our webpage www.dunnlab.de.
Contact:
Dr. Kevin Denkmann • Managing Director
Dunn Labortechnik GmbH • Your Partner for Your Research
Thelenberg 6 • 53567 Asbach • www.dunnlab.de
Tel. +49 (2683) 4 30 94 • E-Mail: info@dunnlab.de