BelloCell® High Density Bioreactor

Bioreactor system with Macrocarriers.

The disposable BelloCell® is based on the concept of bellow-induced alternating flow of media and air through porous BioNoc II® or BioMESH® macorcarriers, where cells reside and grow, providing low shear stress, high aeration and foam-free culture environment, thus enabling culturing of high cell densities.

• Disposable high-yield cell culture system
• Applications: Mammalian and insect cell culture, cell proliferation, cell mass production, generation of recombinant proteins, viruses, production of EVs/exosomes, production of monoclonal antibodies, proteome and drug research, and more
• Systems with or without continuous media recirculation
• Consists of the BelloStage®-3000 compressor, sterile single-use BelloCell® bottles, BioNoc II® or BioMESH®macrocarriers, and optionally the BelloFeeder®-1500 pump
• BioNoc II® macrocarrier made from 100 % PET fibers, pore size 50-200 Μm, non-pyrogenic, autoclavable, specific surface area 2.400 cm²/g, for up to 1 billion cells/g macrocarrier
• BioMESH® macroporous carriers are low-lint grid-like cell culture carriers (pore sizes: PP net 670 Μm/ PET Mesh 200 Μm) with a specific surface area of up to 10.000 cm² per 0,1 liter bed volume and recommended for high cell density harvesting applications
• Different bottles for batch and for continuos cultivation available
• The cell mass produced by one BelloCell® bottle (standard bottle with 5,5 g BioNoc II® macrocarriers) is comparable to 20 - 30 roller bottles

GlucCell®

Glucose monitoring system suitable for serum-containing and serum-free culture media of mammalian, insect and yeast cell culture.

• Palm sized, portable, calibration-free, instantly usable with disposable test strips
• Glucose concentration in mg/dl or mmol/l
• Measuring range: 20 - 600 mg/dl (1,1 - 33,3 mmol/l)
• Precision: > 95 %, Accuracy > 90 %, Linearity: 0.997
• Direct measurement without requirement to separate cells from culture media
• Sample volume: 1.5 Μl
• Test result time: 15 seconds
• Click here for suitable Glucose Test Strips