Gryphon” Modular Microdispenser System

Gryphon” Modular Microdispenser System

– “Crystal Gryphon” – “Gryphon LCP” – “Crystal Gryphon LCP” “Gryphon” general features:
  • No disposables, cutting operating costs
  • The “All-In-One” Microdispenser enables screen and protein drop-setting in one protocol
  • Modular design allows for custom set-ups
  • Versatile and upgradeable
  • Add a nano or LCP dispenser at any point in the future
  • Set up sitting and hanging drop vapour diffusion crystallization experiments
  • Set up batch crystallization drops (under oil)
  • Combines individual precipitant and protein solutions into crystallization trial wells
  • X-Y stage with two plate positions and one wash station
  • Low maintenance
  96 Syringe Head*:
  • 96 flexible Nitinol needles (memory metal)
  • Dispensing accurately 100 nl to 100 Μl volume with a CV of less than 5 %
  • Aspiration from different deep well blocks (e. g. 1 ml and 2 ml)
  • Aspiration from reservoir wells into crystallization wells of one crystallization plate
  • 96 head is suitable for further volume options such as 250 Μl, 500 Μl or 1000 Μl
  • For dispensing buffers and additives
  • *24-syringe head and 384-syringe head are further options
  Compatibility with Plates:
  • Suitable for work with deep well, 96-, 384- and 1536-well plates
  • Compatible with most crystallization plates with up to 5 crystallization wells and one reservoir well
  • Commonly used plates from several companies will be included in the software (ARI Intelli-Plates, Greiner, Swissci MRC, Corning, Molecular Dimension)
  • Further plate definitions can be added in the software
  Nano Protein Dispense Head (optional):
  • Non-contact nano dispenser for dispensing proteins
  • Dispenses 50 nl up to 100 Μl with a CV of less than 5 % (1-, 2- or 3-channels possible)
  • Two options to aspirate/dispense: Air backed and liquid backed
  • Sample recovery possible to minimize total consumption of protein solutions
  LCP (Lipidic Cubic Phase) module (optional):
  • Seeding and for highly viscous samples
  • Syringe based lipidic cubic phase, bicelle dispenser
  • Lipidic sponge-phase screen for membrane proteins
  • Dispenses 25 nl of viscous solutions with a CV < 5%
  • Integrated LCP mixing station
  • Quick change syringe design makes loading the syringe easy
  • Self-aligning syringe needle eliminates the need for constant calibration
  • Aspirate from 0.2 ml tubes with an optionally added longer needle
  • 8 tube positions for seeding applications
  • 96-well sandwich plate ready to seal in less than 2 minutes
  further information about the Gryphon (PDF)
 

Contact Person

Dr. Kevin Denkmann

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